In Vitro System for Studying the Efficacy of Antiviral Agents in Preventing the Reactivation of Latent Herpes Simplex Virus-Reference-Cited by-同舟云学术

In Vitro System for Studying the Efficacy of Antiviral Agents in Preventing the Reactivation of Latent Herpes Simplex Virus

Published:1979-04 Issue:4 Volume:15 Page:625-627
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Wohlenberg Charles¹,Openshaw Harry¹,Notkins Abner L.¹

Affiliation:

1. Laboratory of Oral Medicine, National Institute of Dental Research, Bethesda, Maryland 20205

Abstract

Antiviral antibody and interferon did not prevent in vitro reactivation of herpes simplex virus in latently infected sensory ganglia. Phosphonoacetic acid and 9-β- d -arabinofuranosyladenine blocked reactivation, but this treatment did not eradicate the latent infection.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.15.4.625

Reference22 articles.

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2. Synthesis of herpes simplex virus, vaccinia virus, and adenovirus DNA in isolated HeLa cell nuclei. I. Effect of viral-specific antisera and phosphonoacetic acid;Bolden A.;J. Virol.,1975

3. Activation of latent herpes simplex by trigeminal sensory-root section;Carlton C. A.;N. Engl. J. Med.,1952

4. Fox B. W. 1977. Pharmacology and chemistry of some inhibitors of herpes replication p. 23-32. In J. S. Oxford F. A. Drasar and J. D. Williams (ed.) Chemotherapy of herpes simplex virus infections. Academic Press New York.

5. Antiviral activity of interferons;Friedman R. M.;Bacteriol. Rev.,1977

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