A Novel CovS Variant Harbored by a Colonization Strain Reduces Streptococcus pyogenes Virulence-Reference-Cited by-同舟云学术

A Novel CovS Variant Harbored by a Colonization Strain Reduces Streptococcus pyogenes Virulence

Published:2023-04-25 Issue:4 Volume:205 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Plainvert Céline¹²,Rosinski-Chupin Isabelle³,Weckel Antonin¹,Lambert Clara¹,Touak Gérald²,Sauvage Elisabeth³,Poyart Claire¹²,Glaser Philippe³,Fouet Agnès¹²^ORCID

Affiliation:

1. Université Paris Cité, Institut Cochin, INSERM, U1016, CNRS, UMR8104, Paris, France

2. Service de Bactériologie, CNR des Streptocoques, Hôpitaux Universitaires Paris Centre, Paris, France

3. Institut Pasteur, Ecologie et Evolution de la Résistance aux Antibiotiques, UMR3525, Paris, France

Abstract

Streptococcus pyogenes , also known as group A Streptococcus , causes a wide variety of diseases, leading to 517,000 deaths yearly. The two-component CovRS system, which responds to MgCl 2 and the antimicrobial peptide LL-37, controls the expression of 15% of the genome.

Funder

High Council for Scientific and Technological Cooperation between France-Israel

Centre National de Reference des Streptocoques

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00039-23

Reference78 articles.

1. Pathogenesis of Group A Streptococcal Infections

2. The global burden of group A streptococcal diseases

3. Molecular basis of group A streptococcal virulence

4. Array of M Protein Gene Subtypes in 1064 Recent Invasive Group A Streptococcus Isolates Recovered from the Active Bacterial Core Surveillance

5. Virulence factor regulation and regulatory networks in Streptococcus pyogenes and their impact on pathogen–host interactions

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