The Species-Specific 282 Residue in the PB2 Subunit of the Polymerase Regulates RNA Synthesis and Replication of Influenza A Viruses Infecting Bat and Nonbat Hosts-Reference-Cited by-同舟云学术

The Species-Specific 282 Residue in the PB2 Subunit of the Polymerase Regulates RNA Synthesis and Replication of Influenza A Viruses Infecting Bat and Nonbat Hosts

Published:2022-03-09 Issue:5 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Banerjee Saptarshi¹,De Aratrika¹,Kedia Nandita¹,Bhakta Koustav²,Wang Linfa³^ORCID,Bhattacharjee Bornali⁴,Mondal Arindam¹^ORCID

Affiliation:

1. School of Bioscience, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

2. Department of Biochemistry, Bose Institute, Kolkata, West Bengal, India

3. Duke-NUS Medical School, Singapore City, Singapore

4. Amity Institute of Biotechnology, Amity University Kolkata, Kolkata, West Bengal, India

Abstract

Influenza A viruses are known for their ability to perform cross-species transmission, facilitated by amino acid alterations either in the surface antigen hemagglutinin (HA) or in the polymerase subunit PB2. Recent isolation of influenza A-like viruses from bats raised concern about their epizootic and zoonotic potential.

Funder

Council of Scientific and Industrial Research, India

DST | Science and Engineering Research Board

Department of Biotechnology, Ministry of Science and Technology, India

Ministry of Education, India

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.02190-21

Reference47 articles.