Two-Component Signal Transduction Systems in the Human Pathogen Streptococcus agalactiae

Author:

Thomas Lamar1,Cook Laura1

Affiliation:

1. Binghamton Biofilm Research Center, Department of Biology, Binghamton University, Binghamton, New York, USA

Abstract

Streptococcus agalactiae (group B Streptococcus [GBS]) is an important cause of invasive infection in newborns, maternal women, and older individuals with underlying chronic illnesses. GBS has many mechanisms to adapt and survive in its host, and these mechanisms are often controlled via two-component signal transduction systems. In GBS, more than 20 distinct two-component systems (TCSs) have been classified to date, consisting of canonical TCSs as well as orphan and atypical sensors and regulators.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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