Evaluation of Urinary Elimination of N -Acetyl-β-Glucosaminidase in Healthy Volunteers Treated with Dibekacin or Gentamicin-Reference-Cited by-同舟云学术

Evaluation of Urinary Elimination of N -Acetyl-β-Glucosaminidase in Healthy Volunteers Treated with Dibekacin or Gentamicin

Published:1982-06 Issue:6 Volume:21 Page:1013-1015
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Camí J.¹,Segura J.¹,Baños J. E.¹,Garcia I.¹,Drobnic L.¹

Affiliation:

1. Clinical Pharmacology Unit and Internal Medicine Service, Hospital de Nuestra Señora del Mar, and Department of Pharmacology and Therapeutics, Universidad Autonoma, Barcelona, Spain

Abstract

The urinary excretion of N -acetyl-β-glucosaminidase was studied in healthy subjects during and after treatment with aminoglycosides. In terms of this parameter dibekacin appeared to be less nephrotoxic than gentamicin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.21.6.1013

Reference15 articles.

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3. Antibacterial activity of dibekacin against gentamicin-resistant organisms;Hamada M.;Jpn. J. Antibiot.,1977

4. Hultberg B. N. Norden and P. A. Ockerman. 1972. NOTES 1015

5. Urinary excretion of acid hydrolases in disease. J. Clin.

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