Influenza Virus Infection Impairs the Gut’s Barrier Properties and Favors Secondary Enteric Bacterial Infection through Reduced Production of Short-Chain Fatty Acids-Reference-Cited by-同舟云学术

Influenza Virus Infection Impairs the Gut’s Barrier Properties and Favors Secondary Enteric Bacterial Infection through Reduced Production of Short-Chain Fatty Acids

Published:2021-08-16 Issue:9 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Sencio Valentin¹²³⁴⁵,Gallerand Alexandre⁶,Gomes Machado Marina¹²³⁴⁵,Deruyter Lucie¹²³⁴⁵,Heumel Séverine¹²³⁴⁵,Soulard Daphnée¹²³⁴⁵,Barthelemy Johanna¹²³⁴⁵,Cuinat Céline⁷,Vieira Angelica T.⁶,Barthelemy Adeline¹²³⁴⁵,Tavares Luciana P.⁶,Guinamard Rodolphe⁸,Ivanov Stoyan⁸,Grangette Corinne¹²³⁴⁵,Teixeira Mauro M.⁶,Foligné Benoit⁹,Wolowczuk Isabelle¹²³⁴⁵,Le Goffic Ronan¹⁰,Thomas Muriel⁷,Trottein François¹²³⁴⁵^ORCID

Affiliation:

1. Université Lille, US 41, UMS 2014, PLBS, U1019, UMR 9017, CIIL, Centre d'Infection et d'Immunité de Lille, Lille, France

2. Centre National de la Recherche Scientifique, UMR 9017, Lille, France

3. Institut National de la Santé et de la Recherche Médicale, U1019, Lille, France

4. Centre Hospitalier Universitaire de Lille, Lille, France

5. Institut Pasteur de Lille, Lille, France

6. Centre Méditerranéen de Médecine Moléculaire (C3M), Institut National de la Santé et de la Recherche Médicale U1065, Université Côte d’Azur, Nice, France

7. Micalis Institute, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement UMR1319, AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France

8. Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

9. Université Lille, INSERM, CHU Lille, U995, Lille Inflammation Research International Center (LIRIC), Lille, France

10. Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement UR892, UVSQ, VIM, Jouy-en-Josas, France

Abstract

Along with respiratory tract disease per se , viral respiratory infections can also cause extrapulmonary complications with a potentially critical impact on health. In the present study, we used an experimental model of influenza A virus (IAV) infection to investigate the nature and outcome of the associated gut disorders.

Funder

Agence National pour la Recherche

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00734-20

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