Author:
Poirel Laurent,Dortet Laurent,Bernabeu Sandrine,Nordmann Patrice
Abstract
ABSTRACTGenetic features associated with theblaNDM-1gene were investigated in 6Escherichia coli, 7Klebsiella pneumoniae, 1Citrobacter freundii, 1Proteus mirabilis, and 1Providencia stuartiiisolate of worldwide origin. Clonal diversity was observed for bothE. coliandK. pneumoniae. TheblaNDM-1gene was carried by different plasmid types (IncA/C, IncF, IncL/M, or untypeable) and was likely chromosome borne in two isolates. TheblaNDM-1plasmids coharbored a variety of resistance determinants, including β-lactamase genes, quinolone resistance genes, and 16S RNA methylase genes.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
352 articles.
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