Virus-induced diabetes mellitus. V. Biological differences between the M variant and other strains of encephalomyocarditis virus

Author:

Ross M E,Onodera T,Hayashi K,Notkins A L

Abstract

The M variant of encephalomyocarditis virus is very closely related serologically to five other strains of encephalomyocarditis virus. Despite the serological relationship, these five viruses differ markedly from the M variant in their tissue tropisms and only the M variant infects beta cells of the pancreas, producing diabetes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference8 articles.

1. Virus-induced diabetes mellitus. III. Influence of the sex and strain of the host;Boucher D. W.;J. Infect. Dis.,1975

2. Virus-induced diabetes mellitus. I. Hyperglycemia and hypoinsulinemia in mice infected with encephalomyocarditis virus;Boucher D. W.;J. Exp. Med.,1973

3. Some properties of the encephalomyocarditis, Columbia SK and Mengo viruses;Craighead J. E.;Proc. Soc. Exp. Biol. Med.,1965

4. Diabetes mellitus-like syndrome in mice infected with encephalomyocarditis virus;Craighead J. E.;Am. J. Pathol.,1971

5. The relationship of Mengo Encephalomyelitis, Encephalomyocarditis, Columbia-SK and M.M. viruses;Dick G. W. A.;J. Immunol.,1949

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