Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP-Reference-Cited by-同舟云学术

Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP

Published:2022-05-11 Issue:9 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Rychlowska Malgorzata¹,Agyapong Abigail¹,Weinfeld Michael²,Schang Luis M.¹^ORCID

Affiliation:

1. Baker Institute for Animal Health and Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA

2. Department of Oncology, Division of Experimental Oncology, University of Alberta, Edmonton, Alberta, Canada

Abstract

The 2015–2017 Zika virus (ZIKV) outbreak in Brazil and subsequent international epidemic revealed the strong association between ZIKV infection and congenital malformations, mostly neurodevelopmental defects up to microcephaly. The scale and global expansion of the epidemic, the new ZIKV outbreaks (Kerala state, India, 2021), and the potential burden of future ones pose a serious ongoing risk.

Funder

HHS | National Institutes of Health

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00333-22

Reference136 articles.

1. Anonymous. Pan American Health Organization/World Health Organization. Zika suspected and confirmed cases reported by countries and territories in the Americas Cumulative cases 2015–2017. 2018. Washington D.C.:PAHO/WHO; 2017.

2. Zika Virus (I). Isolations and serological specificity

3. Congenital Zika syndrome: A systematic review

4. Neurological outcomes of congenital Zika syndrome in toddlers and preschoolers: a case series

5. Consequences of congenital Zika virus infection

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular and Cellular Mechanisms Underlying Neurologic Manifestations of Mosquito-Borne Flavivirus Infections;Viruses;2023-10-31

2. DNA damage and repair: underlying mechanisms leading to microcephaly;Frontiers in Cell and Developmental Biology;2023-10-10

3. Potential role of lncRNA in impairing cellular properties of human neural progenitor cells following exposure to Zika virus E protein;Experimental Neurology;2023-10

4. Neurodevelopmental outcomes in congenital and perinatal infections;Current Opinion in Infectious Diseases;2023-07-19

5. Astrocytes derived from neural progenitor cells are susceptible to Zika virus infection;PLOS ONE;2023-03-29