PRRSV Infection Induces Gasdermin D-Driven Pyroptosis of Porcine Alveolar Macrophages through NLRP3 Inflammasome Activation-Reference-Cited by-同舟云学术

PRRSV Infection Induces Gasdermin D-Driven Pyroptosis of Porcine Alveolar Macrophages through NLRP3 Inflammasome Activation

Published:2022-07-27 Issue:14 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

He Sheng¹^ORCID,Li Lu¹,Chen Haifan¹,Hu Xiaoli¹,Wang Wendi¹,Zhang Hui¹,Wei Ruiping¹,Zhang Xiaoxiao¹,Chen Yaosheng¹,Liu Xiaohong¹

Affiliation:

1. State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong, People’s Republic of China

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the pathogens responsible for major economic losses in the global swine industry. Characterizing the detailed process by which PRRSV induces cell death pathways will help us better understand viral pathogenesis and provide implications for therapeutic intervention against PRRSV.

Funder

Agriculture Research System of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.02127-21

Reference76 articles.

1. Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection

2. Reproductive effects of arteriviruses: equine arteritis virus and porcine reproductive and respiratory syndrome virus infections

3. Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States