Porcine Endogenous Retrovirus Transmission Characteristics of an Inbred Herd of Miniature Swine-Reference-Cited by-同舟云学术

Porcine Endogenous Retrovirus Transmission Characteristics of an Inbred Herd of Miniature Swine

Published:2002-03-15 Issue:6 Volume:76 Page:3045-3048
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Oldmixon Beth A.¹,Wood James C.¹,Ericsson Thomas A.¹,Wilson Carolyn A.²,White-Scharf Mary E.³,Andersson Goran³,Greenstein Julia L.¹,Schuurman Henk-Jan¹,Patience Clive¹³

Affiliation:

1. Immerge BioTherapeutics, Inc.

2. Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Federal Drug Administration, Bethesda, Maryland

3. BioTransplant, Inc., Charlestown, Massachusetts

Abstract

ABSTRACT Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.76.6.3045-3048.2002

Reference22 articles.

1. Birmingham, K. 1999. FDA subcommittee finds no evidence of PERV transmission. Nat. Med. 5 : 855.

2. Infection of Nonhuman Primate Cells by Pig Endogenous Retrovirus

3. Boeke, J. D., and J. P. Stoye. 1997. Retrotransposons, endogenous retroviruses, and the evolution of retroelements, p. 343-436. In J. M. Coffin, S. H. Hughes, and H. E. Varmus (ed.), Retroviruses. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.

4. Study of Full-Length Porcine Endogenous Retrovirus Genomes with Envelope Gene Polymorphism in a Specific-Pathogen-Free Large White Swine Herd

5. Cozzi, E., S. Masroor, B. Soin, C. Vial, and D. J. White. 2000. Progress in xenotransplantation. Clin. Nephrol. 53 : 13-18.

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