Shift of excretory-secretory immunogens of Trypanosoma cruzi during human Chagas' disease

Author:

Jazín E E1,Luquetti A O1,Rassi A1,Frasch A C1

Affiliation:

1. Instituto de Investigaciones Bioquímicas, Luis F. Leloir, Fundación Campomar, Buenos Aires, Argentina.

Abstract

We studied secreted-excreted immunogens in human patients infected with Trypanosoma cruzi. A pair of 45- to 55-kDa antigens and a family of shed acute-phase antigens characterized the acute phase, while antibodies against a 160- to 170-kDa immunogen appeared at the chronic phase of the disease.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference15 articles.

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3. Comparative studies on infectivity and surface carbohydrates of several strains of Trypanosoma cruzi;Gonzalez Capa S. M.;Medicina (Buenos Aires),1981

4. Joiner K. A. W. D. daSilva M. T. Rimoldi C. H. Hammer A. Sher and T. L. Kipnis. 1988. Biochemical characterization' of a NOTES 2191

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