Indole Inhibits ToxR Regulon Expression in Vibrio cholerae-Reference-Cited by-同舟云学术

Indole Inhibits ToxR Regulon Expression in Vibrio cholerae

Published:2019-03 Issue:3 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Howard Mondraya F.¹,Bina X. Renee¹,Bina James E.¹

Affiliation:

1. Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Abstract

Indole is a degradation product of tryptophan that functions as a signaling molecule in many bacteria. This includes Vibrio cholerae , where indole was shown to regulate biofilm and type VI secretion in nontoxigenic environmental isolates.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00776-18

Reference66 articles.

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4. Enhanced Interaction of Vibrio cholerae Virulence Regulators TcpP and ToxR under Oxygen-Limiting Conditions

5. A Vibrio cholerae LysR Homolog, AphB, Cooperates with AphA at the tcpPH Promoter To Activate Expression of the ToxR Virulence Cascade

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