Peripheral Merozoite Surface Proteins Are Targets of Naturally Acquired Immunity against Malaria in both India and Ghana

Author:

Garcia-Senosiain Asier12,Kana Ikhlaq Hussain12,Singh Susheel Kumar12,Chourasia Bishwanath Kumar12,Das Manoj Kumar3,Dodoo Daniel4,Singh Subhash5,Adu Bright4,Theisen Michael12

Affiliation:

1. Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

2. Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark

3. National Institute of Malaria Research, Field Unit, Ranchi (Jharkhand), India

4. Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana

5. Indian Institute of Integrative Medicine, Canal Road, Jammu, India

Abstract

Development of a successful blood-stage vaccine against Plasmodium falciparum malaria remains a high priority. Immune-epidemiological studies are effective tools for the identification of antigenic targets of naturally acquired immunity (NAI) against malaria. However, differences in study design and methodology may compromise interstudy comparisons.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

European and Developing Countries Clinical Trials Partnership

Strategiske Forskningsråd

Udenrigsministeriet

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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