Hemoglobin Induces Early and Robust Biofilm Development in Streptococcus pneumoniae by a Pathway That Involves comC but Not the Cognate comDE Two-Component System-Reference-Cited by-同舟云学术

Hemoglobin Induces Early and Robust Biofilm Development in Streptococcus pneumoniae by a Pathway That Involves comC but Not the Cognate comDE Two-Component System

Published:2021-03-17 Issue:4 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Akhter Fahmina¹,Womack Edroyal¹,Vidal Jorge E.²^ORCID,Le Breton Yoann³,McIver Kevin S.³^ORCID,Pawar Shrikant¹,Eichenbaum Zehava¹^ORCID

Affiliation:

1. Department of Biology, Georgia State University, Atlanta, Georgia, USA

2. Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA

3. Department of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland—College Park, College Park, Maryland, USA

Abstract

Streptococcus pneumoniae grows in biofilms during both asymptomatic colonization and infection. Pneumococcal biofilms on abiotic surfaces exhibit delayed growth and lower biomass and lack the structures seen on epithelial cells or during nasopharyngeal carriage.

Funder

US department of Education

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00779-20

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