Penicillinase production and in vitro susceptibilities of Staphylococcus lugdunensis

Author:

Herchline T E1,Barnishan J1,Ayers L W1,Fass R J1

Affiliation:

1. Department of Internal Medicine, Ohio State University College of Medicine, Columbus 43210.

Abstract

Of 59 clinical isolates of Staphylococcus lugdunensis, 76% were beta-lactamase negative, with penicillin G MICs of less than or equal to 0.13 microgram/ml, and 24% were beta-lactamase positive, with penicillin MICs of greater than or equal to 0.5 microgram/ml. Bimodal distributions were observed also with ampicillin, ampicillin-sulbactam, and amoxicillin-clavulanate. All strains were susceptible to oxacillin, cephalothin, gentamicin, rifampin, and vancomycin; 98% were erythromycin susceptible.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference5 articles.

1. In vitro susceptibilities of four species of coagulase-negative staphylococci;Fass R. J.;Antimicrob. Agents Chemother.,1986

2. Clinical isolates of Staphylococcus Iugdunensis sp. nov. and Staphylococcus schleiferi: bacteriological characteristics and susceptibility to antimicrobial agents;Fleurette J.;Res. Microbiol.,1989

3. Staphylococcus Iugdunensis sp. nov. and Staphylococcus schleiferi sp. nov., two species from human clinical specimens;Freney J.;Int. J. Syst. Bacteriol.,1988

4. National Committee for Clinical Laboratory Standards. 1988. Tentative standard M7-T2. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically 2nd ed. National Committee for Clinical Laboratory Standards Villanova Pa.

5. National Committee for Clinical Laboratory Standards. 1988. Tentative standard M2-T4. Performance standards for antimicrobial disk susceptibility tests 4th ed. National Committee for Clinical Laboratory Standards Villanova Pa.

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