Nucleotide sequence of the SHV-5 beta-lactamase gene of a Klebsiella pneumoniae plasmid-Reference-Cited by-同舟云学术

Nucleotide sequence of the SHV-5 beta-lactamase gene of a Klebsiella pneumoniae plasmid

Published:1990-12 Issue:12 Volume:34 Page:2439-2441
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Billot-Klein D¹,Gutmann L¹,Collatz E¹

Affiliation:

1. Laboratoire de Microbiologie Médicale, Université Paris VI, France.

Abstract

The nucleotide sequence of the SHV-5 beta-lactamase gene, subcloned from a plasmid of Klebsiella pneumoniae, was determined. The amino acid changes thought to be responsible for the extended substrate profile of SHV-5 are Gly----Ser234 and Glu----Lys235. SHV-5 is identical to SHV-4, except for Leu----Arg201, which accounts for the difference in apparent pI of the two enzymes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.34.12.2439

Reference20 articles.

1. The structure of 1-lactamases;Ambler R. P.;Philos. Trans. R. Soc. London B,1980

2. Close evolutionary relationship between the chromosomally encoded P-lactamase gene of Klebsiella pneumoniae and the TEM P-lactamase gene mediated by R plasmids;Arakawa Y.;FEBS Lett.,1986

3. Ausubel F. R. Brent R. E. Kingston D. D. Moore J. G. Seidman J. A. Smith and K. Struhl (ed.). 1989. Current protocols in molecular biology. John Wiley & Sons Inc. New York.

4. Single amino acid substitution between SHV-1 P-lactamase and cefotaxime-hydrolyzing SHV-2 enzyme;Barthelemy M.;FEBS Lett.,1988

5. Complete amino acid sequence of p453-plasmid-mediated PIT-2 ,B-lactamase (SHV-1);Barthelemy M.;Biochem. J.,1988

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