Author:
Li Yang,Liu Guangwang,Zhai Zanjing,Liu Lina,Li Haowei,Yang Ke,Tan Lili,Wan Peng,Liu Xuqiang,Ouyang Zhengxiao,Yu Zhifeng,Tang Tingting,Zhu Zhenan,Qu Xinhua,Dai Kerong
Abstract
ABSTRACTPeriprosthetic infection remains a challenging clinical complication. We investigated the antibacterial properties of pure (99.9%) magnesium (Mg)in vitroand in anin vivorat model of implant-related infection. Mg was highly effective against methicillin-resistantStaphylococcus aureus-induced osteomyelitis and improved new peri-implant bone formation. BacterialicaAandagrRNAIII transcription levels were also assessed to characterize the mechanism underlying the antibacterial properties of the Mg implant.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
105 articles.
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