Bioengineering Strategies for Developing Vaccines against Respiratory Viral Diseases

Author:

Iyer Shalini1ORCID,Yadav Rajesh1ORCID,Agarwal Smriti1ORCID,Tripathi Shashank2,Agarwal Rachit1ORCID

Affiliation:

1. Center for BioSystems Science and Engineering, Indian Institute of Science, Bengaluru, India

2. Department of Microbiology and Cell Biology, Center for Infectious Disease Research, Indian Institute of Science, Bengaluru, India

Abstract

Respiratory viral pathogens like influenza and coronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused outbreaks leading to millions of deaths. Vaccinations are, to date, the best and most economical way to control such outbreaks and have been highly successful for several pathogens. Currently used vaccines for respiratory viral pathogens are primarily live attenuated or inactivated and can risk reversion to virulence or confer inadequate immunity.

Funder

Indian Institute of Science

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Reference234 articles.

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