Immunophenotyping and Transcriptional Profiling of Human Plasmablasts in Dengue-Reference-Cited by-同舟云学术

Immunophenotyping and Transcriptional Profiling of Human Plasmablasts in Dengue

Published:2021-11-09 Issue:23 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Aggarwal Charu¹,Saini Keshav¹^ORCID,Reddy Elluri Seetharami¹²,Singla Mohit³,Nayak Kaustuv¹^ORCID,Chawla Yadya M.¹,Maheshwari Deepti¹,Singh Prabhat¹,Sharma Pragati¹⁴,Bhatnagar Priya¹⁵,Kumar Sanjeev¹^ORCID,Gottimukkala Kamalvishnu¹,Panda Harekrushna¹,Gunisetty Sivaram⁶,Davis Carl W.⁷,Kissick Haydn Thomas⁸,Kabra Sushil Kumar³,Lodha Rakesh³,Medigeshi Guruprasad R.⁹^ORCID,Ahmed Rafi⁷⁸,Murali-Krishna Kaja¹⁶⁷,Chandele Anmol¹^ORCID

Affiliation:

1. ICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology, New Delhi, India

2. Kusuma School of Biological Sciences, Indian Institute of Technology, New Delhi, India

3. Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India

4. Department of Biotechnology, School of Chemical and Life Sciences, New Delhi, India

5. TERI School of Advanced Studies, New Delhi, India

6. Department of Pediatrics, Division of Infectious Disease, Emory University School of Medicine, Atlanta, Georgia, USA

7. Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, USA

8. Department of Microbiology, Emory University School of Medicine, Atlanta, Georgia, USA

9. Translational Health Science and Technology Institute, Faridabad, Haryana, India

Abstract

Dengue is globally spreading, with over 100 million clinical cases annually, with symptoms ranging from mild self-limiting febrile illness to more severe and sometimes life-threatening dengue hemorrhagic fever or shock, especially among children. The pathophysiology of dengue is complex and remains poorly understood despite many advances indicating a key role for antibody-dependent enhancement of infection.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00610-21

Reference108 articles.

1. The global distribution and burden of dengue

2. Dengue--How Best to Classify It