Long Dissociation of Bictegravir from HIV-1 Integrase-DNA Complexes
Author:
Affiliation:
1. Gilead Sciences, Inc., Foster City, California, USA
2. McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital and Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada
Abstract
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Link
https://journals.asm.org/doi/pdf/10.1128/AAC.02406-20
Reference25 articles.
1. Retroviral DNA Integration
2. Structural basis of second-generation HIV integrase inhibitor action and viral resistance
3. Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes
4. Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile
5. Susceptibility to HIV-1 integrase strand transfer inhibitors (INSTIs) in highly treatment-experienced patients who failed an INSTI-based regimen
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