Paerucumarin, a New Metabolite Produced by the pvc Gene Cluster from Pseudomonas aeruginosa-Reference-Cited by-同舟云学术

Paerucumarin, a New Metabolite Produced by the pvc Gene Cluster from Pseudomonas aeruginosa

Published:2008-10-15 Issue:20 Volume:190 Page:6927-6930
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Clarke-Pearson Michael F.¹,Brady Sean F.¹

Affiliation:

1. Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, 1230 York Avenue, New York, New York 10065

Abstract

ABSTRACT The pvc gene cluster from Pseudomonas aeruginosa has been linked to the biosynthesis of both the pyoverdine chromophore and pseudoverdine. Our reinvestigation of the role this gene cluster plays in P. aeruginosa secondary metabolite biosynthesis shows that its major product is actually paerucumarin, a novel isonitrile functionalized cumarin.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00801-08

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