Author:
Buckley H R,Price M R,Daneo-Moore L
Abstract
During the course of Candida albicans antigen production, a variant of this organism was encountered which did not produce hyphae at 37 degrees C. Presented here are some of the characteristics of this variant. It produces hyphae at 25 degrees C on cornmeal agar and synthetic medium plus N-acetylglucosamine and Tween 80. At 37 degrees C, it does not produce hyphae on these media, although C. albicans normally does produce hyphae under these circumstances. In liquid synthetic medium, this variant does not produce hyphae at 37 degrees C. The variant strain was analyzed for DNA, RNA, protein content, and particle size. After 50 to 70 h in balanced exponential-phase growth, particle size distribution was narrow, and there were no differences in the DNA, RNA, or protein content per particle in the two strains. When balanced exponential-phase cultures were brought into stationary phase, both strains contained the same amount of DNA per cell.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference19 articles.
1. Germ tube and chlamydospore formation by Canididai albicans in a new medium;Beheshti F.;J. Clin. Microbiol.,1975
2. The identification of Candida albicanis within two hours by the use of an egg white slide preparation;Buckley H. R.;Sabouraudia,1963
3. A study of the conditions and mechanism of the dephenylamine reaction for the colorimetric estimation of deoxyribonucleic acid;Burton K.;Biochem. J.,1956
4. Synthesis of nucleic acids and proteins in dimorphic forms of Candida albicans;Dabrowa N.;Sabouraudia,1970
5. The effect of growth medium on filament production in Candida albicans;Evans E. G. V.;Sabouraudia,1974
Cited by
31 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献