Stimulation of Resistance of Immunocompromised Mice by a Muramyl Dipeptide Analog-Reference-Cited by-同舟云学术

Stimulation of Resistance of Immunocompromised Mice by a Muramyl Dipeptide Analog

Published:1982-09 Issue:3 Volume:37 Page:1285-1288
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Osada Yasuaki¹,Mitsuyama Masao²,Matsumoto Kensuke¹,Une Tsutomu¹,Otani Tsuyoshi¹,Ogawa Hidemasa¹,Nomoto Kikuo²

Affiliation:

1. Research Institute, Daiichi Seiyaku Company, Ltd., 1-16-13 Kitakasai, Edogawa-ku, Tokyo 132, Japan

2. Department of Microbiology, School of Medicine, Kyushu University, Fukuoka, Japan

Abstract

L18-MDP(Ala), a synthetic derivative of muramyl dipeptide, enhanced resistance against Escherichia coli and Candida albicans infections in aged mice and younger adult mice whose defense mechanism(s) had been depressed by X-ray irradiation or by treatment with cyclophosphamide.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.37.3.1285-1288.1982

Reference18 articles.

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3. Enhancement of nonspecific immunity to Klebsiella pneumoniae infection by a synthetic immunoadjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine) and several analogs;Chedid L.;Proc. Nati. Acad. Sci. U.S.A.,1977

4. Lung damage from cytotoxic drugs;CoIls C. H.;Cancer Chemother. Pharmacol.,1980

5. Activation of macrophages for enhanced release of superoxide anion and greater killing of Candida albicans by injection of muramyl dipeptide;Cummings N. P.;J. Exp. Med.,1980

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