Abstract
Antiserum to mannophosphoinositides had a significant inhibitory effect on phospholipid synthesis in Mycobacterium smegmatis ATCC 607 at different phases of growth; however, the inhibition was more pronounced in the exponential phase. The rate of synthesis of total phospholipids and individual phospholipids, viz., cardiolipin, phosphatidylethanolamine, and mannophosphoinositides, decreased in the presence of antiserum as compared with normal serum. The maximum inhibitory effect of antiserum was exerted on the synthesis of mannophosphoinositides, particularly on tetraacylated dimannophosphoinositide. Antiserum also had a growth inhibitory effect as compared with normal serum.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference29 articles.
1. Immune reactivities of antibodies against glycolipids. I. Properties of antigalactocerebroside antibodies purified by a novel technique of affinity binding to liposomes;AlMing C. R.;Immunochemistry,1977
2. Biosynthesis of mannophosphoinositides of Mycobacterium phlei;Ballou C. E.;Methods Enzymol.,1972
3. Antigenicity of phosphatidylinositomannosides of mycobacteria;Banerjee B.;Immunochemistry,1978
4. Lesions in Escherichia coli membranes after action of antibody and complement;Bladen H. A.;J. Bacteriol.,1966
5. Kinetics of the bactericidal action of normal serum on gram-negative bacteria;Davis S. D.;J. Immunol.,1965
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献