Formylglycine-Generating Enzyme-Like Proteins Constitute a Novel Family of Widespread Type VI Secretion System Immunity Proteins-Reference-Cited by-同舟云学术

Formylglycine-Generating Enzyme-Like Proteins Constitute a Novel Family of Widespread Type VI Secretion System Immunity Proteins

Published:2021-10-12 Issue:21 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Lopez Juvenal¹,Le Nguyen-Hung¹,Moon Ki Hwan¹^ORCID,Salomon Dor²,Bosis Eran³,Feldman Mario F.¹

Affiliation:

1. Department of Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA

2. Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

3. Department of Biotechnology Engineering, ORT Braude College of Engineering, Karmiel, Israel

Abstract

Despite the wealth of knowledge on the diversity of biochemical activities carried out by T6SS effectors, comparably little is known about the various strategies that bacteria employ to prevent susceptibility to T6SS-dependent bacterial killing. Our work establishes a novel family of T6SS immunity proteins with a characteristic FGE domain.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00281-21

Reference94 articles.

1. Secretion systems in Gram-negative bacteria: structural and mechanistic insights

2. Tn-Seq Analysis of Vibrio cholerae Intestinal Colonization Reveals a Role for T6SS-Mediated Antibacterial Activity in the Host

3. SalmonellaTyphimurium utilizes a T6SS-mediated antibacterial weapon to establish in the host gut

4. T6SS: The bacterial "fight club" in the host gut

5. Shigella sonnei Encodes a Functional T6SS Used for Interbacterial Competition and Niche Occupancy

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