A BALB/c congenic strain of mice that carries a genetic locus (Ityr) controlling resistance to intracellular parasites-Reference-Cited by-同舟云学术

A BALB/c congenic strain of mice that carries a genetic locus (Ityr) controlling resistance to intracellular parasites

Published:1983-06 Issue:3 Volume:40 Page:1234-1235
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Potter M,O'Brien A D,Skamene E,Gros P,Forget A,Kongshavn P A,Wax J S

Abstract

BALB/c.DBA/2 Idh-1b-Ityr-Pep-3b congenic mice were developed by introgressively backcrossing the Idh-1b and Pep-3b markers of DBA/2 mice onto the BALB/c pi mice. This introduced a 30-centimorgan chromosome 1 segment of DBA/2 chromatin that contained the Ityr gene. BALB/c.DBA/2 Idh-1b-Ityr-Pep-3b mice were resistant to in vivo infections by Salmonella typhimurium, Mycobacterium bovis, and Leishmania donovani.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.40.3.1234-1235.1983

Reference12 articles.

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5. Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice;Gros P.;J. Immunol.,1981

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