The ADP-Heptose Biosynthesis Enzyme GmhB is a Conserved Gram-Negative Bacteremia Fitness Factor-Reference-Cited by-同舟云学术

The ADP-Heptose Biosynthesis Enzyme GmhB is a Conserved Gram-Negative Bacteremia Fitness Factor

Published:2022-07-21 Issue:7 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Holmes Caitlyn L.¹²^ORCID,Smith Sara N.²,Gurczynski Stephen J.²,Severin Geoffrey B.²^ORCID,Unverdorben Lavinia V.¹²,Vornhagen Jay¹²,Mobley Harry L. T.²,Bachman Michael A.¹²^ORCID

Affiliation:

1. Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA

2. Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA

Abstract

Klebsiella pneumoniae is a leading cause of Gram-negative bacteremia, which is a major source of morbidity and mortality worldwide. Gram-negative bacteremia requires three major steps: primary site infection, dissemination to the blood, and bloodstream survival.

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

HHS | NIH | National Heart, Lung, and Blood Institute

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00224-22

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