Affiliation:
1. Massachusetts General Hospital Boston, Massachusetts 02114
Abstract
Pseudomonas aeruginosa
strain GN315, producing kanamycin acetyltransferase, can transmit a plasmid determining resistance to kanamycin, amikacin (BB-K8), butirosin, tobramycin, and sisomicin, but not gentamicin, to other pseudomonas strains. This plasmid, pMG5, belongs to the same incompatibility group as plasmids determining gentamicin resistance in
P. aeruginosa
via gentamicin acetyltransferase I. Like other members of this group, it also confers resistance to Hg
2+
, organomercurials, and certain deoxyribonucleic acid phages. When pMG5 is introduced into a cell carrying a related R factor, some transconjugants can subsequently cotransfer new combinations of resistance determinants as though recombinant plasmids had been formed.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
47 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献