Direct Inhibition of RetS Synthesis by RsmA Contributes to Homeostasis of the <i>Pseudomonas aeruginosa</i> Gac/Rsm Signaling System-Reference-Cited by-同舟云学术

Direct Inhibition of RetS Synthesis by RsmA Contributes to Homeostasis of the Pseudomonas aeruginosa Gac/Rsm Signaling System

Published:2022-03-15 Issue:3 Volume:204 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Corley Jodi M.¹^ORCID,Intile Peter¹,Yahr Timothy L.¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA

Abstract

The Pseudomonas aeruginosa Gac/Rsm system controls ∼500 genes and governs a critical lifestyle switch by inversely regulating factors that favor acute or chronic colonization. Control of gene expression by the Gac/Rsm system is mediated through RsmA and RsmF, small RNA-binding proteins that interact with target mRNAs to inhibit or promote protein synthesis and/or mRNA stability.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00580-21

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