Evaluation of a Rapid PCR Assay for Diagnosis of Meningococcal Meningitis-Reference-Cited by-同舟云学术

Evaluation of a Rapid PCR Assay for Diagnosis of Meningococcal Meningitis

Published:2003-08 Issue:8 Volume:41 Page:3851-3853
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Richardson David C.¹,Louie Lisa¹,Louie Marie¹,Simor Andrew E.¹

Affiliation:

1. Sunnybrook and Women's College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

Abstract

ABSTRACT We compared the results of Gram staining and culture of cerebrospinal fluid to results obtained with a rapid PCR assay for the diagnosis of meningococcal meningitis in 281 cases of suspected bacterial meningitis. PCR had a sensitivity of 97% compared to a sensitivity of 55% for culture, and the PCR specificity was 99.6%. PCR results were available within 2 h of the start of the assay.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.41.8.3851-3853.2003

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