Identification of the Hypervirulent Lineages of Neisseria meningitidis , the ST-8 and ST-11 Complexes, by Using Monoclonal Antibodies Specific to Nme DI

Author:

Claus Heike1,Weinand Hanne1,Frosch Matthias1,Vogel Ulrich1

Affiliation:

1. Institute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

Abstract

ABSTRACT Most cases of serogroup C meningococcal disease are caused by the clonal lineages ST-8 and ST-11. The gene encoding the putative restriction-modification system Nme DI is specific to these lineages. We report here a monoclonal antibody directed against the Nme DI endonuclease as a tool for their rapid and spe-cific identification.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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