The Emergence, Diversification, and Transmission of Subgroup J Avian Leukosis Virus Reveals that the Live Chicken Trade Plays a Critical Role in the Adaption and Endemicity of Viruses to the Yellow-Chickens

Author:

Deng Qiaomu1,Li Qiuhong1,Li Min1,Zhang Shengbin2,Wang Peikun3,Fu Fumei1,Zhu Weiyu1,Wei Tianchao1,Mo Meilan1ORCID,Huang Teng1,Zhang Huanmin4,Wei Ping1ORCID

Affiliation:

1. Institute for Poultry Science and Health, Guangxi University, Nanning, China

2. Guangxi State Farm Yongxin Husbandry Group of Xijiang Co., Ltd., Guigang, China

3. Institute of Microbe and Host Health, Linyi University, Linyi, China

4. USDA, Agricultural Research Service, Avian Disease and Oncology Laboratory, East Lansing, Michigan, USA

Abstract

Although the general epidemiology of ALV-J is well studied, the ongoing evolutionary and transmission dynamics of the virus remain poorly investigated. The phylogenetic differences and relationship of the clades and subclades were characterized, and the epidemics and factors driving the geographical spread and inter-host transmission of different ALV-J clades were explored for the first time.

Funder

Guangxi Program for Modern Agricultural Industry Technical System Construction-Chicken Industry

Guangxi Special Funding on Science and Technology Research

Shandong Provincial Natural Science Foundation

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference66 articles.

1. ICTV. 2020. International committee on taxonomy of viruses. Virus taxonomy: 2019 release. https://talk.ictvonline.org/taxonomy/.

2. Studies of the Genomic RNA of Leukosis Viruses: Implications for RNA Dimerization

3. Nair V, Fadly AM, et al. 2013. Leukosis/sarcoma group, p 553–592. In Swayne DE (ed) Diseases of poultry, 13th ed. Wiley, Blackwell, Ames, IA.

4. Vertical transmission of avian leukosis virus subgroup J (ALV-J) from hens infected through artificial insemination with ALV-J infected semen

5. Vertical transmission of ALV from ALV-J positive parents caused severe immunosuppression and significantly reduced marek’s disease vaccine efficacy in three-yellow chickens

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