Affiliation:
1. Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park 16802, USA.
Abstract
An Arthrobacter beta-galactosidase has homology with the lysosomal acid beta-galactosidases from humans and mice and with a Xanthomonas manihotis enzyme. Phylogenetic analysis of the deduced amino acid sequence showed an unusual pattern, with this procaryotic enzyme clustering within the animal clade. The gene encodes a subunit of 52 kDa, and the enzyme appears to be active as a dimer. The enzyme hydrolyzed substrates with either a beta-1,4 or a beta-1,3 linkage.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
27 articles.
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