Affiliation:
1. Research Laboratories, Toyama Chemical Co., Ltd., Toyama 930-8508, Japan
Abstract
ABSTRACT
The
gyrA
and
gyrB
genes of
Chlamydia pneumoniae
TW-183 were cloned, and their proteins were purified by use of a fusion system with a maltose-binding protein. The 50% inhibitory concentrations of garenoxacin, sparfloxacin, moxifloxacin, gatifloxacin, and levofloxacin were 10.1, 47.5, 39.6, 64.2, and 156.9 μg/ml, respectively, and the MICs against
C. pneumoniae
TW-183 were 0.008, 0.016, 0.063, 0.125, and 0.25 μg/ml, respectively.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
22 articles.
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