Complete Genome Sequence of Hypervirulent Streptococcus pyogenes emm 3 Strain 1838

Author:

Lei Benfang1,Flores Anthony R.2,Yeoman Carl3,Liu Mengyao1

Affiliation:

1. Department of Microbiology and Immunology, Montana State University, Bozeman, Montana, USA

2. Division of Infectious Diseases, Department of Pediatrics, Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA

3. Department of Animal & Range Sciences, Montana State University, Bozeman, Montana, USA

Abstract

We report the complete genome sequence for Streptococcus pyogenes strain 1838 (type emm 3) isolated from a patient with toxic shock syndrome. The strain lacked the speK - and sla -encoding prophage frequently encountered among emm 3 strains and possessed an Arg66His mutation in CovR of the 2-component virulence regulatory system CovRS.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

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