TCS01 Two-Component System Influenced the Virulence of Streptococcus pneumoniae by Regulating PcpA

Author:

Yu Wei-Li1,Pan Jin-Ge1,Qin Ru-Xue1,Lu Zhong-Hua1,Bai Xiao-Hui2,Sun Yun1

Affiliation:

1. The First Department of Intensive Care Unit, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

2. College of Life and Environment Sciences, Huangshan University, Huangshan, Anhui, China

Abstract

Streptococcus pneumoniae relies on two-component systems (TCSs) to regulate the processes of pathogenicity, osmotic pressure, chemotaxis, and energy metabolism. The TCS01 system of S. pneumoniae is composed of HK01 (histidine kinase) and RR01 (response regulator).

Funder

National Natural Science Foundation of China

Excellent Young Talents Support Program of Universities

National Natural Science Foundation Incubation Plan of the Second Hospital of Anhui Medical University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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