Affiliation:
1. Department of Clinical Virology, Göteborg University, S-413 46 Göteborg, Sweden
Abstract
ABSTRACT
Recently, three distinct genotypes of clinical herpes simplex virus type 1 (HSV-1) isolates were identified based on DNA sequence information and phylogenetic analysis of clinical isolates and laboratory strains. We utilized single-nucleotide polymorphism within the genes coding for glycoproteins G and I for rapid genotype classification by PCR and restriction enzyme cleavage. The method is suitable for high-scale genotyping of clinical HSV-1 isolates and for the detection of recombinants.
Publisher
American Society for Microbiology
Cited by
52 articles.
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