Discrepancies and Interpretation Problems in Susceptibility Testing of VIM-1-Producing Klebsiella pneumoniae Isolates

Author:

Giakkoupi P.1,Tzouvelekis L. S.2,Daikos G. L.3,Miriagou V.4,Petrikkos G.3,Legakis N. J.2,Vatopoulos A. C.1

Affiliation:

1. Department of Microbiology, National School of Public Health

2. Department of Microbiology

3. 1st Department of Propaedeutic Medicine, Medical School of Athens

4. Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece

Abstract

ABSTRACT Susceptibilities to β-lactam antibiotics of five VIM-1-producing Klebsiella pneumoniae isolates were determined by broth microdilution, Etest, disk diffusion, and the automated systems Vitek 2, Phoenix, and MicroScan. Significant discrepancies were observed in the determination of susceptibility to imipenem and meropenem. Interpretation problems by the automated systems were also noted.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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