New Quinolone Resistance Phenomenon in Salmonella enterica : Nalidixic Acid-Susceptible Isolates with Reduced Fluoroquinolone Susceptibility

Author:

Hakanen Antti J.12,Lindgren Marianne1,Huovinen Pentti1,Jalava Jari3,Siitonen Anja4,Kotilainen Pirkko12

Affiliation:

1. Antimicrobial Research Laboratory

2. Department of Medicine, Turku University Hospital, Turku, Finland

3. Laboratory of Human Microbial Ecology

4. Enteric Bacteria Laboratory, Department of Bacterial and Inflammatory Diseases, National Public Health Institute, Turku and Helsinki

Abstract

ABSTRACT We describe the emergence of a new quinolone resistance pattern in Salmonella enterica isolates from Southeast Asia. These isolates are susceptible to nalidixic acid but exhibit reduced susceptibility to ciprofloxacin. The increase of such strains may threaten the value of the nalidixic acid disk test to screen for reduced fluoroquinolone susceptibility in salmonellas.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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