Induction of T Helper Type 1 Responses by a Polysaccharide Deacetylase from Cryptococcus neoformans-Reference-Cited by-同舟云学术

Induction of T Helper Type 1 Responses by a Polysaccharide Deacetylase from Cryptococcus neoformans

Published:2003-09 Issue:9 Volume:71 Page:5412-5417
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Biondo Carmelo¹,Beninati Concetta¹,Bombaci Mauro¹,Messina Luciano¹,Mancuso Giuseppe¹,Midiri Angelina¹,Galbo Roberta¹,Teti Giuseppe¹

Affiliation:

1. Dipartimento di Patologia e Microbiologia Sperimentale, Facoltà di Medicina e Chirurgia, Università di Messina, I-98125 Messina, Italy

Abstract

ABSTRACT A 25-kDa cryptococcal deacetylase (d25) was found here to induce cell proliferation, as well as secretion of interleukin 2 and gamma interferon, but not interleukin 4, in spleen cells from d25-immunized or Cryptococcus neoformans -infected mice. The gamma interferon, but not the interleukin 2, response was required for the protective activities of d25 immunization in a murine cryptococcosis model.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.71.9.5412-5417.2003

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