Neodymium as Metal Cofactor for Biological Methanol Oxidation: Structure and Kinetics of an XoxF1-Type Methanol Dehydrogenase

Author:

Schmitz Rob A.1ORCID,Picone Nunzia1,Singer Helena2,Dietl Andreas3,Seifert Kerstin-Anikó3,Pol Arjan1,Jetten Mike S. M.1ORCID,Barends Thomas R. M.3,Daumann Lena J.2ORCID,Op den Camp Huub J. M.1ORCID

Affiliation:

1. Department of Microbiology, Radboud University, Nijmegen, The Netherlands

2. Department Chemie, Ludwig-Maximilians-Universität München, Munich, Germany

3. Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Heidelberg, Germany

Abstract

Lanthanides comprise a group of 15 elements with atomic numbers 57 to 71 that are essential in a variety of high-tech devices, such as mobile phones, but were considered biologically inert for a long time. The biological relevance of lanthanides became evident when the acidophilic methanotroph Methylacidiphilum fumariolicum SolV, isolated from a volcanic mud pot, could only grow when lanthanides were supplied to the growth medium.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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