Profiles of Local and Systemic Inflammation in the Outcome of Treatment of Human Cutaneous Leishmaniasis Caused by Leishmania ( Viannia )

Author:

Navas Adriana12,Fernández Olga12,Gallego-Marín Carolina1,Castro María del Mar12,Rosales-Chilama Mariana12,Murillo Julieth13,Cossio Alexandra12,McMahon-Pratt Diane4,Saravia Nancy Gore12,Gómez María Adelaida12

Affiliation:

1. Centro Internacional de Entrenamiento e Investigaciones Médicas-CIDEIM, Cali, Colombia

2. Universidad Icesi, Cali, Colombia

3. Universidad Javeriana, Cali, Colombia

4. Yale School of Public Health, New Haven, Connecticut, USA

Abstract

The immune mechanisms that contribute to the efficacy of treatment of cutaneous leishmaniasis (CL) are not fully understood. The aim of this study was to define immune correlates of the outcome of treatment of CL caused by Leishmania ( Viannia ) species during standard of care treatment with pentavalent antimonials.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | Fogarty International Center

Departamento Administrativo de Ciencia, Tecnología e Innovación

Wellcome Trust

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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