High Proportion of Genome-Wide Homology and Increased Pretreatment pvcrt Levels in Plasmodium vivax Late Recurrences: a Chloroquine Therapeutic Efficacy Study-Reference-Cited by-同舟云学术

High Proportion of Genome-Wide Homology and Increased Pretreatment pvcrt Levels in Plasmodium vivax Late Recurrences: a Chloroquine Therapeutic Efficacy Study

Published:2021-07-16 Issue:8 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Rovira-Vallbona Eduard¹^ORCID,Van Hong Nguyen²,Kattenberg Johanna H.¹,Huan Ro Mah³,Binh Nguyen Thi Huong²,Ngọc Nguyen Thi Hong²,Guetens Pieter¹,Hieu Nguyen Luong²,Hien Nguyen Thị Thu²,Sang Vu Thi²,Long Nguyen Duc²,Sauve Erin¹,Duong Tran Thanh²,Xa Nguyen Xuan²,Erhart Annette¹⁴,Rosanas-Urgell Anna¹^ORCID

Affiliation:

1. Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium

2. National Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam

3. Centre for Disease Control and Prevention, Pleiku, Gia Lai, Vietnam

4. Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia

Abstract

Chloroquine (CQ) is the first-line treatment for Plasmodium vivax malaria in most countries where malaria is endemic. Monitoring P. vivax CQ resistance (CQR) is critical but remains challenged by the difficulty to distinguish real treatment failure from reinfection or liver relapse.

Funder

Belgium Development Cooperation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00095-21

Reference58 articles.

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5. World Health Organization. 2009. Methods for surveillance of antimalarial drug efficacy. https://www.who.int/malaria/publications/atoz/9789241597531/en/

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