Differential Susceptibilities of Anopheles albimanus and Anopheles pseudopunctipennis to Infections with Coindigenous Plasmodium vivax Variants VK210 and VK247 in Southern Mexico

Author:

Gonzalez-Ceron Lilia1,Rodriguez Mario H.2,Nettel Jose C.1,Villarreal Cuauhtemoc1,Kain Kevin C.3,Hernandez Juan E.4

Affiliation:

1. Centro de Investigación de Paludismo,1

2. Centro de Investigaciones Sobre Enfermedades Infecciosas,2 and

3. Tropical Diseases Unit, The Toronto Hospital and The University of Toronto, Toronto, Canada3

4. Department of Informatics,4 Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico, and

Abstract

ABSTRACT The susceptibilities to coindigenous Plasmodium vivax of colonized Anopheles albimanus and Anopheles pseudopunctipennis from southern Mexico were investigated by simultaneous feeding with infected blood obtained from patients. The genes encoding circumsporozoite protein variant types (VK210 and VK247) in blood samples were determined by PCR and oligonucleotide probe hybridization. A. albimanus was more susceptible to VK210, and A. pseudopunctipennis was more susceptible to VK247.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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