Affiliation:
1. Institut für Mikrobiologie, Heinrich-Heine-Universität, D-40225 Düsseldorf, Germany
Abstract
ABSTRACT
Chlamydospore formation of the fungal pathogen
Candida albicans
was found to depend on the Efg1 protein, which regulates the yeast-hyphal transition. Isogenic mutants lacking
EFG1
or encoding T206A and T206E variants did not differentiate chlamydospores, while
cek1
,
cph1
, or
tpk2
mutations had no effect. Furthermore, filamentation of
efg1 cph1
double mutants in microaerophilic conditions suggests a novel Efg1p/Cph1p-independent filamentation pathway in
C. albicans.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Cited by
117 articles.
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