Antibiotic Synergism Against Listeria monocytogenes-Reference-Cited by-同舟云学术

Antibiotic Synergism Against Listeria monocytogenes

Published:1972-01 Issue:1 Volume:1 Page:30-34
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Moellering Robert C.¹²³⁴,Medoff Gerald¹²³⁴,Leech Irene¹²³⁴,Wennersten Christine¹²³⁴,Kunz Lawrence J.¹²³⁴

Affiliation:

1. Infectious Disease Unit, Children's Service, and Bacteriology Laboratory, Massachusetts General Hospital, Boston, Massachusetts 02114

2. Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115

3. Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115

4. Department of Microbiology, Harvard Medical School, Boston, Massachusetts 02115

Abstract

The effectiveness of ampicillin, penicillin, streptomycin, and gentamicin against 20 strains of Listeria monocytogenes was studied in vitro. For all strains, the minimal bactericidal concentration (MBC) of both ampicillin and penicillin was much higher than the minimal inhibitory concentration (MIC). The MBC of both streptomycin and gentamicin was close to the MIC, but relatively high concentrations of these antibiotics were necessary to inhibit the growth of most of the strains of Listeria . The combination of penicillin plus streptomycin was synergistic against 19 of 20 strains and in the remaining strain produced enhanced killing (but of less magnitude than our criterion for synergism). Combinations of penicillin plus gentamicin, ampicillin plus streptomycin, and ampicillin plus gentamicin produced enhanced killing against all strains tested. No antagonism was observed when ampicillin or penicillin was combined with streptomycin or gentamicin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.1.1.30

Reference14 articles.

1. Clinical and laboratory aspects of Listeria m1ontocytogenes infections with a report of ten cases;Buchner L.;Amer. J. Med.,1968

2. The dose, distribtution, and excretion of gentarnicin with special reference to renal failure;Gingell J. C.;J. Infec. Dis.,1969

3. Ampicillin treatment of listeriosis;Gordon R. C.;J. Pediat.,1970

4. Die in-vitro-Empfindlichkeit von Listeria monocytogenes (Pinie) gegen Sulfonomide und Antibiotica. Zentralbl. Bakteriol. Parasitenk. lnfektionskr;Linzenmeier G.;Hyg. Abt. I Orig.,1954

5. Listeriosis complicating maligniant diseatse. A new associaition;Louria D. B.;Ann Intern. Med.,1967

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