Genomic Epidemiology of Carbapenemase-Producing Enterobacterales at a Hospital System in Toronto, Ontario, Canada, 2007 to 2018-Reference-Cited by-同舟云学术

Genomic Epidemiology of Carbapenemase-Producing Enterobacterales at a Hospital System in Toronto, Ontario, Canada, 2007 to 2018

Published:2021-07-16 Issue:8 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Jamal Alainna J.¹²^ORCID,Mataseje Laura F.³,Williams Victoria⁴,Leis Jerome A.¹⁴,Tijet Nathalie⁵,Zittermann Sandra⁵,Melano Roberto G.⁵^ORCID,Mulvey Michael R.³,Katz Kevin⁴,Allen Vanessa G.⁴,McGeer Allison J.¹²

Affiliation:

1. Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

2. Sinai Health System, Toronto, Ontario, Canada

3. National Microbiology Laboratory, Winnipeg, Manitoba, Canada

4. Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

5. Public Health Ontario Laboratory, Toronto, Ontario, Canada

Abstract

At a hospital system (H1) in ON, Canada, we investigated whether whole-genome sequencing (WGS) altered initial epidemiological interpretation of carbapenemase-producing Enterobacterales (CPE) transmission. We included patients with CPE colonization/infection identified by population-based surveillance from October 2007 to August 2018 who received health care at H1 in the year before/after CPE detection. H1 reported epidemiological transmission clusters.

Funder

Government of Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00360-21

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