Focusing the Lens on the CAMERA Concepts: Early Combination β-Lactam and Vancomycin Therapy in Methicillin-Resistant Staphylococcus aureus Bacteremia-Reference-Cited by-同舟云学术

Focusing the Lens on the CAMERA Concepts: Early Combination β-Lactam and Vancomycin Therapy in Methicillin-Resistant Staphylococcus aureus Bacteremia

Published:2020-06-23 Issue:7 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Wilsey H Andrew¹^ORCID,Burgess Donna R.²³,Burgess David S.³

Affiliation:

1. Department of Pharmacy Practice, Binghamton University School of Pharmacy and Pharmaceutical Sciences, Binghamton, New York, USA

2. University of Kentucky, UK HealthCare, Lexington, Kentucky, USA

3. University of Kentucky, College of Pharmacy, Lexington, Kentucky, USA

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) has grown to become a major burden on health care systems. The cumulation of limited therapeutic options and worsened patient outcomes with persistent MRSA bacteremia has driven research in optimizing its initial management. The guidelines published by the Infectious Diseases Society of America currently recommend combination therapy for refractory MRSA bacteremia, but the utility of combining antibiotics from the start of therapy is under investigation.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00360-20

Reference48 articles.

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3. Limitations of Vancomycin in the Management of Resistant Staphylococcal Infections

4. Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

5. Resistance of Staphylococcus aureus to the Action of Penicillin.

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