Body Surface Area-Based Dosing Regimen of Caspofungin in Children: a Population Pharmacokinetics Confirmatory Study-Reference-Cited by-同舟云学术

Body Surface Area-Based Dosing Regimen of Caspofungin in Children: a Population Pharmacokinetics Confirmatory Study

Published:2019-07 Issue:7 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Yang Xin-Mei¹,Leroux Stephanie²³,Storme Thomas²,Zhang Dao-Lun²,de Beaumais Tiphaine Adam⁴,Shi Hai-Yan¹,Yang Yi-Lei¹,Wang Xiao-Ling⁵,Zhao Wei¹⁶^ORCID,Jacqz-Aigrain Evelyne²⁷

Affiliation:

1. Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China

2. Department of Pediatric Pharmacology and Pharmacogenetics, Hôpital Robert Debré, APHP, Paris, France

3. Neonatal Intensive Care Unit, CHU de Rennes, Rennes, France

4. Precision Cancer Medicine Team, Institut Gustave Roussy, Villejuif, France

5. Clinical Research Center, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing, China

6. Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, China

7. University Paris Diderot, Sorbonne Paris-Cité, Paris, France

Abstract

We evaluated the population pharmacokinetics of caspofungin in children (2 to 12 years of age). The real-world data from 48 children were best fit by a two-compartment model with first-order elimination.

Funder

Ministry of Science and Technology of the People's Republic of China

Shandong University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00248-19

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2. Advances in Antifungal Therapy